Which of the following can be symptoms of Type 3 hypersensitivity reaction?

In a Type 3 hypersensitivity reaction, the immune system forms antigen-antibody complexes that can precipitate in various tissues, leading to inflammatory responses and tissue damage. Symptoms can manifest in different ways depending on the organs affected by these complexes.

Arthralgia, or joint pain, is a classic symptom associated with Type 3 hypersensitivity due to the deposition of immune complexes in the joints, leading to inflammation and discomfort. This condition is often observed in autoimmune diseases where such complexes are prevalent.

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the presence of antibodies that can form these immune complexes. The resulting inflammation can affect multiple systems, including the joints, kidneys, skin, and more, showcasing the systemic nature of this hypersensitivity reaction.

Therefore, both arthralgia and systemic lupus erythematosus are related to the processes involved in Type 3 hypersensitivity reactions, confirming that the correct answer encompasses both symptoms associated with this type of immune response. This highlights the connection between immune complexes and the resultant clinical manifestations in affected individuals.